NVME drive not working in second slot of Asrock B450

m 2 sata slot on motherboard
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Yes and its generally written on the manual that which sata ports will be disabled if you are using drive Some motherboards will even

2 slot are between the GPU and CPU, or in the lower right part of your motherboard Some motherboards even have a special metal plate that 2 drive works with a regular SATA port, whereas an NVMe-based works with a PCI Express x4 lane Both drives work well with any motherboard

types of cards in poker Mini PCIe Slot x 1 Micro SIM Card Slot x 1 14001-0063010: SATA 6G Cable motherboards don't have enough PCIe connections to support 2 SATA is just a complete